Topic 1: Single Gene

During this session, we will focus on exploring genes and inheritance patterns.

We will use a virtual lab program to experiment with Drosophila genetics.

Activities and Assignments

Assignment 1: Having "Pun" with Punnett Squares.

Punnett Squares can be used to predict the probability of producing offspring with specific genotypes/ phenotypes. For this assignment, we will use Punnett Squares to make predictions about the inheritance pattern of the genetic disorder sickle cell anemia.

To begin, complete the following activities:
Read:
Text pages 351-355.


Sites to visit:

Punnett Square tutorial 1:
http://www.biology.arizona.edu/mendelian_genetics/problem_sets/monohybrid_cross/01t.html


Punnett Square tutorial 2:
http://www2.edc.org/weblabs/Punnett/punnettsquares.html


Monohybrid Cross and Punnett Squares
http://wps.prenhall.com/esm_klug_essentials_5/0,8785,1170646-content,00.html <---Take post-quiz: 3.1 Monohybrid Cross and Punnett Squares and write down your answers. You will turn this in to Ms. Johnson.


Discussion

Sickle cell anemia (SCA) is a human genetic disorder caused by a recessive allele (so "normal" would be dominant). A couple wants to know the probability that they will have a child affected by SCA.

For each scenario, what are the chances that this couple will have a child with sickle cell anemia? Create a punnett square for each scenario and bring your results to class.

1) Both the man and woman are normal, but each has one affected parent and one normal parent with no family history of SCA.

2) The man is affected by SCA; the normal woman has no family history of SCA.

3) Both the man and woman are affected by SCA.


TO BE TURNED IN ON TUESDAY, APRIL 27th
-Answers to "Post Quiz 3.1"
-Answers to sickle cell scenarios 1, 2, and 3